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Optimized Conjugation Solution for Precise Extrahepatic Delivery of Small Nucleic Acid Drug
Targeted delivery enhances the safety and efficacy of small nucleic acid drug. By conjugating siRNA or ASO with targeting molecules- such as antibodies or peptides- cellular uptake, stability, and bioavailability are improved, while immunogenicity and toxicity are reduced.
In this webinar, we’ll introduce technical solutions and application cases for small RNA drug conjugation, focusing on conjugate product identification, precise delivery and gene silencing, and differences across methods, offering new insights to boost research efficiency.
The topics that we will cover include:
- Advances in Small Nucleic Acid Drug Delivery
- Ligand-Mediated Extrahepatic Delivery Techniques
- Advantages of DAR 1 Antibody-siRNA Conjugate
- GenScript Conjugation Solutions for Accelerating Precise Targeted Delivery
Attendees will learn about:
Conjugation methods, applications, and clinical progress of small nucleic acid drug conjugates.Characterization of conjugated products using SDS-PAGE, CE-SDS, SEC, IEX, and MS.Characterization of conjugated products using SDS-PAGE, CE-SDS, SEC, IEX, and MS.GenScript offers versatile conjugation solutions tailored to AOC/POC requirements, delivering high-purity conjugated products with precise silencing efficiency.
Webinar Details
- Date: October 28, 2025
- Time: 2:00 pm EDT / 11:00 am PDT / 8:00 pm CEST
Jacob Guo Ph.D.
Director, Nucleic Acid Platform R&D Department, GenScript
Dr. Jacob Guo is the Director of the Nucleic Acid R&D Platform at GenScript’s Life Science Group, with over a decade of experience in oligonucleotide synthesis. His research focuses on synthetic long oligonucleotides and bioconjugation of nucleic acid drugs.
Jacob holds a PhD in Chemistry from the University of Georgia and has published five first-author papers in high-impact journals, along with submitting several patents related to oligonucleotide bioconjugation and diagnostic applications.Audience summary
Beginners or experts interested in the development of small nucleic acid drugs, particularly in delivery strategies. Audiences focusing on AOC, POC, and conjugated products of siRNA/ASO with other molecules.
Coverage: biotech and biopharma companies, universities, research Institutes, hospital/medical centers.
- Students and researchers interested in small nucleic acid drugs
- Academic researchers and laboratory directors currently in the field of small nucleic acid drugs, particularly delivery strategies
- Research scientists, senior scientists, or project leaders from the R&D department engaged in small nucleic acid drug projects, especially delivery strategies and want to learn more
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