Application Solutions » mRNA Therapeutic Solutions

Overview

mRNA therapeutics represent a groundbreaking class of medicines that use messenger RNA (mRNA) to instruct the body’s own cells to produce specific, functional proteins — unlocking powerful new possibilities in disease treatment and prevention.

Why mRNA?

  • Innovative Mechanism: Delivers genetic instructions, not proteins — enabling cells to produce the therapeutic protein naturally.
  • Proven Safety: Non-integrating and transient, mRNA works safely within the cytoplasm and degrades after use.
  • Unmatched Versatility: Highly programmable for rapid design, scalable manufacturing, and faster therapeutic development.
  • Easy, cost-effective, and scalable: mRNA therapeutics use cell-free synthesis for rapid, economical production from research to large-scale manufacturing

The versatility of mRNA makes it ideal for a wide range of therapeutic applications, driving innovation across multiple fields:

mRNA Applications
Application Solutions

GenScript mRNA Therapeutic Solutions

mRNA Construct Optimization 1
Custom IVT mRNA Synthesis 2
mRNA Delivery Solution 3
mRNA QC Services 4

mRNA Construct Optimization

Custom IVT mRNA Synthesis

mRNA Delivery Solution

mRNA QC Services

mRNA Catalog Products – high quality, ready to use

Products Format Target
Reporter gene mRNA Linear mRNA Liver
Gene editing mRNA Circular RNA Spleen
Antigen mRNA Self-amplifying RNA (saRNA) T-Cells
Gene replacement mRNA LNP formulations CD34+
Ladders & Standards mRNA Targeted LNP
ReadyEdit LNP

Gene Therapy Resources

Brochure mRNA
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mRNA Case Study Report

Case studies showing high expression efficiency of GenScript’s mRNA for expressing SB transposase, GFP, Luciferase, eSpCas9, and more.

Free Download

Circular RNA Case Study Report

Circular RNA introduction, GenScript offering details, and case studies showing increased stability, prolonged expression, and lower immunogenicity compared to linear IVT mRNA.

Free Download

LNP Case Study Report

Case studies demonstrating encapsulation and delivery efficiency of GenScript’s new LNP formulations in cell models, and mouse models via both IM and IV.

Free Download

Critical Consideration in Sourcing mRNA_Whitepaper

This whitepaper provides valuable insights into the essential factors that vaccine and therapy developers should consider when exploring mRNA solutions

Free Download

Advancements in mRNA manufacturing_eBook

Get GenScript’s free application eBook on therapeutics development with mRNA manufacturing solutions

Free Download

mRNA Therapy Modalities_Infographic

Learn about key structural features and functions of IVT mRNA and LNP, therapeutic modalities beyond prophylactic vaccines, mRNA candidates progressing through clinical trials.

Free Download

mRNA Parts_Infographic

Learn about the main structural components of mRNA, the functional roles of each part, what constitutes high-quality IVT mRNA and more.

Free Download

Circular RNA Beginner’s Guide_Infographic

Learn about key structural components of circRNA, the process by which circRNA is translated into protein, and more.

Free Download

Self-Amplifying RNA Beginner’s Guide_Infographic

Learn about key structural components of saRNA, the processes by which saRNA replicates and is translated into protein, and more.

Free Download
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